RFT for the Supply, Delivery, Installation, Commissioning and Calibration of Isothermal Titration Calorimeter (ITC) for Protein Complexes for Trinity College Dublin
Education Procurement Service (EPS)
Trinity College Dublin require the supply of Isothermal Titration Calorimeter (ITC) for protein complexes for the deliverables of a Research Ireland grant. The calorimeter is required for measuring micro-calories of heat evolved or absorbed from protein-protein and protein-small molecule interactions in aqueous solution. The measurement involves multiple injections of ligand (protein, other macromolecules, small molecules) into a cell containing another protein, small molecule, or other macromolecules. The titration is performed under isothermal conditions using a reference cell containing water or related aqueous solution that is similar to the experimental cell. Changes in temperature between the two cells during injections are rapidly equilibrated using active power compensation that is calibrated for calories of heat. The properties of the isothermal titration calorimeter should include the following: (1) The tenderer SHOULD provide a new or recent state-of the-art (ex-demo) model ITC calorimeter, and if ex-demo, it should be minimally used. Volume of experimental and reference cells should be approximately 200 mico-Liters. (2) Typical concentration ranges for analyses should ideally be in the range from 1 micro-Molar to 100 micro-Molar for macromolecules (typically proteins) in the cell, and 10 micro-Molar to 1M concentrations in the injections syringe for the ligand. (3) Preferred temperature range for isothermal titrations from 4 deg Celsius to 60 deg Celsius. (4) software that can analyse data and determine the Kd (dissociation constant), enthalpy, and entropy from analyses of the titrations. (5) Software should handle simple 1:1 binding models, with the possibility to analyse more complex interactions, such as multiple binding sites, sequential interactions. The capability to analyse complex binding with rigor would be a major advantage, as many interactions are not simple 1:1. (6) minimal generation of bubbles or artefactual heat, which may arise from high concentrations of viscous protein in cell (7) Ideally - prefer system/software compatibility with .opj files generated by Origin 7 (or later) software, since we have nearly 20 years of previous data collections. This could be transferred to new control computer for continuity. (8) New computer, drivers, and accessories required to run the calorimeter software.
DeadlineThe time limit for receipt of tenders was 2026-05-12. The procurement was published on 2026-04-20.
Who? What?- โข Detection and analysis apparatus โบ Analysis apparatus
- โข Laboratory, optical and precision equipments (excl. glasses) โบ Checking and testing apparatus
- โข Metering instruments โบ Calorimeters
- โข Aฯฯฮนฮบฮฎ โบ ฮฯฯฮตฮนฮฟฯ ฮคฮฟฮผฮญฮฑฯ ฮฮธฮทฮฝฯฮฝ
- โข Eastern and Midland โบ Dublin
- โข Southern โบ Mid-West
| Date | Document |
|---|---|
| 2026-04-20 | Contract notice |
Object
Scope of the procurement
Title: RFT for the Supply, Delivery, Installation, Commissioning and Calibration of Isothermal Titration Calorimeter (ITC) for Protein Complexes for Trinity College Dublin
Short description:
โTrinity College Dublin require the supply of Isothermal Titration Calorimeter (ITC) for protein complexes for the deliverables of a Research Ireland grant....โ
Type of contract: Supplies
Products/services: Laboratory, optical and precision equipments (excl. glasses) ๐ฆ
Estimated value excluding VAT: 75 700 EUR ๐ฐ
Description
Internal identifier:
0
Estimated value excluding VAT: 75 700 EUR ๐ฐ
Description of the procurement:
โTrinity College Dublin require the supply of Isothermal Titration Calorimeter (ITC) for protein complexes for the deliverables of a Research Ireland grant....โ
Type of contract: Supplies
Products/services: Laboratory, optical and precision equipments (excl. glasses) ๐ฆ
Additional products/services: Calorimeters ๐ฆ
Analysis apparatus ๐ฆ
Checking and testing apparatus ๐ฆ
Country: Ireland ๐ฎ๐ช
Place of performance: Dublin ๐๏ธ
Duration: 24 (MONTH)
The time frame below is expressed in number of months.
Title
Lot Identification Number: LOT-0001
Scope of the procurement
Additional products/services: Calorimeters ๐ฆ
Analysis apparatus ๐ฆ
Checking and testing apparatus ๐ฆ
Procedure
Type of procedure
Open procedure โ
Legal basis: Directive 2014/24/EU
Administrative information
Time limit for receipt of tenders or requests to participate: 2026-05-12 12:00:00 ๐
Conditions for opening of tenders: 2026-05-12 12:30:00 ๐
Conditions for opening of tenders (place): https://www.etenders.gov.ie/epps/cft/prepareViewCfTWS.do?resourceId=7942566
Languages in which tenders or requests to participate may be submitted: English ๐ฃ๏ธ
Minimum time frame during which the tenderer must maintain the tender: 12
Tendering terms
Tenderers may submit more than one tender
Opening date: 2026-05-12 12:30:00 ๐
Place:
โhttps://www.etenders.gov.ie/epps/cft/prepareViewCfTWS.do?resourceId=7942566โ
Languages in which tenders or requests to participate may be submitted: English ๐ฃ๏ธ
Deadline for requesting additional information: 2026-05-05 12:00:00 ๐
Contracting authority
Name and addresses
Name: Education Procurement Service (EPS)
National registration number: IE 6609370 G
Postal address: Castletroy Limerick
Postal code: V94 DK53
Postal town: Limerick
Region: Mid-West ๐๏ธ
Country: Ireland ๐ฎ๐ช
E-mail: info@educationprocurementservice.ie ๐ง
Phone: 061 234 283 ๐
URL: https://www.educationprocurementservice.ie/ ๐
Address of the buyer profile: https://www.educationprocurementservice.ie/ ๐
Type of the contracting authority
Body governed by public law
Main activity
Education
Communication
Documents URL: https://www.etenders.gov.ie/epps/cft/listContractDocuments.do?resourceId=7942566 ๐
Participation URL: https://www.etenders.gov.ie/epps/cft/viewTenders.do?resourceId=7942566 ๐
Electronic submission: Required
Complementary information
Review body
Name: The High Court of Ireland
National registration number: The High Court of Ireland
Department: The High Court of Ireland
Postal address: Four Courts, Inns Quay, Dublin 7
Postal code: D07 WDX8
Postal town: Dublin
Region: Dublin ๐๏ธ
Country: Ireland ๐ฎ๐ช
E-mail: highcourtcentraloffice@courts.ie ๐ง
Phone: +353 1 8886000 ๐
Service from which information about the review procedure may be obtained
Name: The High Court of Ireland
National registration number: The High Court of Ireland
Department: The High Court of Ireland
Postal address: Four Courts, Inns Quay, Dublin 7
Postal code: D07 WDX8
Postal town: Dublin
Region: Dublin ๐๏ธ
Country: Ireland ๐ฎ๐ช
E-mail: highcourtcentraloffice@courts.ie ๐ง
Phone: +353 1 8886000 ๐
Source: OJS 2026/S 077-269946 (2026-04-20)
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